[ccp4bb] homology modeling

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

- CCP4BB

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Scientists position - Australian Synchrotron
From: Sonya Sivaraj Sonya {- dot -} Sivaraj {- at -} SYNCHROTRON {- dot -} ORG {- dot -} AU
Date: 2009-05-04

Next message:
Subject: Re: homology modeling
From: "Chen, Yu Wai" yu-wai {- dot -} chen {- at -} KCL {- dot -} AC {- dot -} UK
Date: 2009-05-05

Subject: homology modeling
From: rui ruisher {- at -} GMAIL {- dot -} COM
Date: 2009-05-04

Hi, All
Suppose I have two proteins A and B, they are structurally homologous,
however the sequence identity is only about 20%. A has crystal structure
available, so if I want to model protein B, what's the best way to do it? I
don't think I can just thread the sequence of B to A structure because the
number of residues are different and there might be gaps and insertions in
the alignment. Any suggestions of good programs?

Thanks.

Rui

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Scientists position - Australian Synchrotron
From: Sonya Sivaraj Sonya {- dot -} Sivaraj {- at -} SYNCHROTRON {- dot -} ORG {- dot -} AU
Date: 2009-05-04

Next message:
Subject: Re: homology modeling
From: "Chen, Yu Wai" yu-wai {- dot -} chen {- at -} KCL {- dot -} AC {- dot -} UK
Date: 2009-05-05