Re: [ccp4bb] homology modeling

- Protein crystallography

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- Protein purification
- Crystallisation

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: homology modeling
From: rui ruisher {- at -} GMAIL {- dot -} COM
Date: 2009-05-04

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Subject: Re: homology modeling
From: "Francisco J {- dot -} Enguita" fenguita {- at -} ITQB {- dot -} UNL {- dot -} PT
Date: 2009-05-05

Subject: Re: homology modeling
From: "Chen, Yu Wai" yu-wai {- dot -} chen {- at -} KCL {- dot -} AC {- dot -} UK
Date: 2009-05-05

I would recommend Modeller
http://www.salilab.org/modeller/

Wai
> Suppose I have two proteins A and B, they are structurally homologous,
> however the sequence identity is only about 20%. A has crystal
> structure available, so if I want to model protein B, what's the best
> way to do it? I don't think I can just thread the sequence of B to A
> structure because the number of residues are different and there might
> be gaps and insertions in the alignment. Any suggestions of good programs?
>

--
Yu Wai Chen, PhD........................................Lecturer
King's College London, Randall Division +44-207-848-8206
New Hunt's House, Guy's Campus, London SE1 1UL, U.K.

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: homology modeling
From: rui ruisher {- at -} GMAIL {- dot -} COM
Date: 2009-05-04

Next message:
Subject: Re: homology modeling
From: "Francisco J {- dot -} Enguita" fenguita {- at -} ITQB {- dot -} UNL {- dot -} PT
Date: 2009-05-05