Re: [ccp4bb] His-His H-bond

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: His-His H-bond
From: Wim Burmeister wpb {- at -} EMBL-GRENOBLE {- dot -} FR
Date: 2007-05-23

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Subject: Simultaneous PHENIX and CCP4 burp
From: Frank von Delft frank {- dot -} vondelft {- at -} SGC {- dot -} OX {- dot -} AC {- dot -} UK
Date: 2007-05-23

Subject: Re: His-His H-bond
From: "V {- dot -} S {- dot -} Gowri" gowri {- at -} MBU {- dot -} IISC {- dot -} ERNET {- dot -} IN
Date: 2007-05-23

Hi,

Please see the following reference. Does this answer your query?

http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1999/121/i22/abs/ja990340o.html

regards,
gowri.

--
V.S. Gowri,
Ph.D Student,
Prof. N. Srinivasan's Lab,
Molecular Biophysics Unit,
Indian Institute of Science,
Bangalore - 560 012.
Karnataka, India.

Voice: 2293 2837 (Lab)
Email: gowri@mbu.iisc.ernet.in, vsgowri@gmail.com

visit: www.sankalpindia.net

========================================================================================================================

> Dear All,
>
> We have solved a structure that has an intersubunit His-His H-bond
> (ND1---NE2). The protein most likely undergoes conformational changes
> that involve the making and breaking of H-bonds at this interface. In
> all the protein structures I have previously studied I don't recall ever
> seeing such a bond - His-His ring stacking yes, but never H-bonding. I
> was wondering if anyone else had seen this type of interaction and
> whether it had any functional significance. The crystals were grown at
> pH 5.6.
>
> Many thanks
>
> Dave Lawson
>
> -------------------------------
>
> Dr. David M. Lawson
> Biological Chemistry Dept.,
> John Innes Centre,
> Norwich,
> NR4 7UH, UK.
> Tel: +44-(0)1603-450725
> Fax: +44-(0)1603-450018
> Email: david.lawson@bbsrc.ac.uk
> Web: http://www.jic.bbsrc.ac.uk/staff/david-lawson/index.htm
>
>
> --
> This message has been scanned for viruses and
> dangerous content by MailScanner, and is
> believed to be clean.
>
>

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: His-His H-bond
From: Wim Burmeister wpb {- at -} EMBL-GRENOBLE {- dot -} FR
Date: 2007-05-23

Next message:
Subject: Simultaneous PHENIX and CCP4 burp
From: Frank von Delft frank {- dot -} vondelft {- at -} SGC {- dot -} OX {- dot -} AC {- dot -} UK
Date: 2007-05-23