Re: [ccp4bb] can glucose covalently bond to the guanidino nitrogen of arginine?

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Fw: temporary position - GlaxoSmithKline - protein crystallography laboratory
From: " Benjamin Bax
Date: 2007-05-24

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Subject: SUMMARY: His-His H-bond
From: "david lawson (JIC)" david {- dot -} lawson {- at -} BBSRC {- dot -} AC {- dot -} UK
Date: 2007-05-24

Subject: Re: can glucose covalently bond to the guanidino nitrogen of arginine?
From: Jawahar Swaminathan jawahar {- at -} EBI {- dot -} AC {- dot -} UK
Date: 2007-05-24

Dear Michael,
I did a quick check of the bonds found between GLC/BGC (alpha-D and
beta-D-glucoses) and Arginine using the MSDSite service at

http://www.ebi.ac.uk/msd-srv/msdsite/

From the left panel if you choose Ligand Bonds and put in GLC
BGC in
the ligand box and ARG in the residue box, there are 1160 interactions
between ARG and the ligand in the PDB but none of these interactions
appear to be covalent. Most interactions between the guanidino nitrogens
and the sugar are either hydrogen bonds or vanderWaals interaction.
Clicking on any of the bars in the result graph will take you to the
list of entries where these interactions can be found.

best regards,

Jawahar Swaminathan
MSD Group
European Bioinformatics Institute

Michael Colaneri wrote:
> Dear colleagues,
>
> Has anyone seen a glucose covalently bonded to the guanidino nitrogens
> of Arginine via a glycosidic bond?
>
> Thanks.
>
> Mike Colaneri
>

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Fw: temporary position - GlaxoSmithKline - protein crystallography laboratory
From: " Benjamin Bax
Date: 2007-05-24

Next message:
Subject: SUMMARY: His-His H-bond
From: "david lawson (JIC)" david {- dot -} lawson {- at -} BBSRC {- dot -} AC {- dot -} UK
Date: 2007-05-24