Re: [ccp4bb] multi-domain protein with identical tertiary structure

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: multi-domain protein with identical tertiary structure
From: Charlie Bond Charles {- dot -} Bond {- at -} UWA {- dot -} EDU {- dot -} AU
Date: 2009-07-02

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From: Christine Bentz Christine {- dot -} Bentz {- at -} HELMHOLTZ-HZI {- dot -} DE
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Subject: Re: multi-domain protein with identical tertiary structure
From: Shankar Prasad Kanaujia spkanaujia {- at -} GMAIL {- dot -} COM
Date: 2009-07-02

thank you all for quick answers.

-shankar

On Thu, Jul 2, 2009 at 12:47 PM, Charlie Bond wrote:

> Depending on your definition of 'identical', examples of repeated gene
> duplication contribute to these:
>
> You could look at glyoxalases where there are dimeric examples where each
> monomer is composed of a repeated subdomain (A1-A2:A1-A2) and monomeric
> examples where a further duplication has occurred (A1-A2-A3-A4)
> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1169964
> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1217405
>
> There are also a number of nucleic acid binding proteins which have strings
> of domains (e.g. zinc finger or RRM domains)
> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1217405
> http://www.ncbi.nlm.nih.gov/pubmed/9305981
>
> Depending on your definition of 'domain', pretty much every repeat-protein
> (e.g. TPR, WD40 etc) could fall under this category.
>
> Cheers,
> Charlie
>
>
> Shankar Prasad Kanaujia wrote:
>
>> Dear CCP4 users,
>> Is there any multi-domain protein (with at least two domains) which has
>> identical tertiary structure of each domain ?
>>
>> Thanking you.
>>
>> -regards
>> shankar
>>
>>
>>
> --
> Charlie Bond
> Professorial Fellow
> University of Western Australia
> School of Biomedical, Biomolecular and Chemical Sciences
> M310
> 35 Stirling Highway
> Crawley WA 6009
> Australia
> Charles.Bond@uwa.edu.au
> +61 8 6488 4406
>
>

--
Yours Sincerely,
Shankar Prasad Kanaujia
Research Student
C/O - Dr. K. Sekar
Bioinformatics Centre, SERC
Indian Institute of Science, Bangalore-12
Phone - 9480258032
Office - 080-2293-3059

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: multi-domain protein with identical tertiary structure
From: Charlie Bond Charles {- dot -} Bond {- at -} UWA {- dot -} EDU {- dot -} AU
Date: 2009-07-02

Next message:
Subject: 3 positions in Hamburg/Germany
From: Christine Bentz Christine {- dot -} Bentz {- at -} HELMHOLTZ-HZI {- dot -} DE
Date: 2009-07-02