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[ccp4bb] Heavy atom derivatives for large structures |
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CCP4bb navigationCCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999Subject: Heavy atom derivatives for large structures From: "George M {- dot -} Sheldrick" gsheldr {- at -} SHELX {- dot -} UNI-AC {- dot -} GWDG {- dot -} DE Date: 2009-08-04 Why is the tantalum bromide cluster the cluster derivative of choice for phasing large structures? As a inorganic chemist (in a previous incarnation) I can think of a lot of other possible clusters that might be suitable. I even have money from a bioinorganic grant that could finance a PhD student from October 1st to work on a project with me in Goettingen to investigate other clusters. In view of the recent success of Tobias Beck's 'magic triangle' phasing reagent I think that clusters containing several heavy atoms might well be worth another look with modern phasing methods (potential applicants should contact me by email). George Prof. George M. Sheldrick FRS Dept. Structural Chemistry, University of Goettingen, Tammannstr. 4, D37077 Goettingen, Germany Tel. +49-551-39-3021 or -3068 Fax. +49-551-39-22582 CCP4bb navigationCCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999 |
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