Quick navigation: Home   |    Site Map   ||    References   |    Biography   ||    Copyright   |    Other copyright   |    Contact us   |    Advert   |   
 

[ccp4bb] Heavy atom derivatives for large structures

- Protein crystallography

Main steps:

   - Protein purification
   - Crystallisation

Special:

   - Programs for crystallography
   - X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

   - CCP4BB

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: detergent crystals
From: Parveen Goyal parveenbmb {- at -} GMAIL {- dot -} COM
Date: 2009-08-04
Next message:
Subject: Re: detergent crystals
From: Leigh Rees leigh {- dot -} rees {- at -} OXFORD-DIFFRACTION {- dot -} COM
Date: 2009-08-04


Subject: Heavy atom derivatives for large structures
From: "George M {- dot -} Sheldrick" gsheldr {- at -} SHELX {- dot -} UNI-AC {- dot -} GWDG {- dot -} DE
Date: 2009-08-04

Why is the tantalum bromide cluster the cluster derivative of
choice for phasing large structures? As a inorganic chemist
(in a previous incarnation) I can think of a lot of other
possible clusters that might be suitable. I even have money
from a bioinorganic grant that could finance a PhD student
from October 1st to work on a project with me in Goettingen
to investigate other clusters. In view of the recent
success of Tobias Beck's 'magic triangle' phasing reagent I
think that clusters containing several heavy atoms might well
be worth another look with modern phasing methods (potential
applicants should contact me by email).

George

Prof. George M. Sheldrick FRS
Dept. Structural Chemistry,
University of Goettingen,
Tammannstr. 4,
D37077 Goettingen, Germany
Tel. +49-551-39-3021 or -3068
Fax. +49-551-39-22582

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: detergent crystals
From: Parveen Goyal parveenbmb {- at -} GMAIL {- dot -} COM
Date: 2009-08-04
Next message:
Subject: Re: detergent crystals
From: Leigh Rees leigh {- dot -} rees {- at -} OXFORD-DIFFRACTION {- dot -} COM
Date: 2009-08-04



ProteinCrystallography.org: Copyright 2006-2010 by Quid United Ltd