[ccp4bb] offtopic: screening compounds libraries for binding via crystallography

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: trouble running coot on MacOSX 10.5
From: Pierre Aller paller {- at -} UVM {- dot -} EDU
Date: 2009-10-28

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Subject: offtopic: screening compounds libraries for binding via crystallography
From: Francis E Reyes Francis {- dot -} Reyes {- at -} COLORADO {- dot -} EDU
Date: 2009-10-28

Hi All

I'm interested in screening small molecule libraries against my xtal
for potential binders. There are many papers that cover this (http://www.nature.com/nbt/journal/v18/n10/abs/nbt1000_1105.html
, for example).

If you have had experience in this field, please email me privately as
I would first like to see how feasible it is to perform these
experiments (especially on an academic budget).

Thanks!

FR

---------------------------------------------
Francis Reyes M.Sc.
215 UCB
University of Colorado at Boulder

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CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: trouble running coot on MacOSX 10.5
From: Pierre Aller paller {- at -} UVM {- dot -} EDU
Date: 2009-10-28

Next message:
Subject: data reduction
From: Alexandra Deaconescu deacona {- at -} BRANDEIS {- dot -} EDU
Date: 2009-10-28