Re: [ccp4bb] unknown density

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: PDB SEGID Case Sensitivity
From: James Stroud xtald00d {- at -} GMAIL {- dot -} COM
Date: 2010-02-03

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Subject: Re: unknown density
From: "Mayer, Mark (NIH/NICHD) [E]" mayerm {- at -} MAIL {- dot -} NIH {- dot -} GOV
Date: 2010-02-03

Subject: Re: unknown density
From: Bostjan Kobe b {- dot -} kobe {- at -} UQ {- dot -} EDU {- dot -} AU
Date: 2010-02-03

I think there is at least one more option here (relevant at least in some
rare cases):
Identifying what that something is likely to be can be significant and may
advance your career

Of course it is important to present supporting or otherwise evidence for
the interpretation. As already discussed, this is difficult in a PDB file,
and that¹s why the accompanying publication can be very important.

Bostjan

On 4/02/10 3:54 AM, "Bernhard Rupp" wrote:

> General remark if I may
> Putting nothing in:
> no significant effect on model and life in general
> Putting Œsomething¹ potentially wrong and misleading in:
> could be detrimental to your career
>
> BR
>
>
> From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Katja
> Schleider
> Sent: Wednesday, February 03, 2010 9:18 AM
> To: CCP4BB@JISCMAIL.AC.UK
> Subject: [ccp4bb] unknown density
>
>
> Dear all,
>
> I found some fairly substantial density in the active site of my protein
> structure. But I don´t know what it should be. My crystallisation condition
> consists of lithium sulfate, citrate-phosphate and peg1000. The whole lot
> doesn't make a dashed bit of sense! Any suggestions to fill this density with
> something?
> Picture is attached.
>
> Thanks a lot,
>
> Katja
>
> __________________________________________________
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---
Bostjan Kobe
ARC Federation Fellow
Professor of Structural Biology
School of Chemistry and Molecular Biosciences
and Institute for Molecular Bioscience (Division of Chemistry and
Structural Biology)
Cooper Road
University of Queensland
Brisbane, Queensland 4072
Australia
Phone: +61 7 3365 2132
Fax: +61 7 3365 4699
E-mail: b.kobe@uq.edu.au
URL: http://profiles.bacs.uq.edu.au/Bostjan.Kobe.html
Office: Building 76 Room 329
Notice: If you receive this e-mail by mistake, please notify me, and do not
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represents only the views of the Sender and not the views of The University
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CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: PDB SEGID Case Sensitivity
From: James Stroud xtald00d {- at -} GMAIL {- dot -} COM
Date: 2010-02-03

Next message:
Subject: Re: unknown density
From: "Mayer, Mark (NIH/NICHD) [E]" mayerm {- at -} MAIL {- dot -} NIH {- dot -} GOV
Date: 2010-02-03