Re: [ccp4bb] The importance of USING our validation tools

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: The importance of USING our validation tools
From: Peter Keller pkeller {- at -} GLOBALPHASING {- dot -} COM
Date: 2007-08-16

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Subject: Re: The importance of USING our validation tools
From: "Mark J {- dot -} van Raaij" vanraaij {- at -} USC {- dot -} ES
Date: 2007-08-16

Subject: Re: The importance of USING our validation tools
From: Jacob Keller j-keller2 {- at -} MD {- dot -} NORTHWESTERN {- dot -} EDU
Date: 2007-08-16

Hello All,

This debacle is actually quite reminiscent of a similar incident that Wayne Hendrickson caught in
the 1970's concerning purported "tRNA crystals." Turned out to be completely fabricated, and the
guy's career went down the drain, I think. A good example to tell your trainees.

Jacob Keller

The ref's:

1. True identity of a diffraction pattern attributed to valyl tRNA

WAYNE A. HENDRICKSON, BROR E. STRANDBERG, ANDERS LILJAS, L. MARIO AMZEL, EATON E. LATTMAN

CONTEXT: SIR - We have examined in detail several publications by H.H. Paradies. One is a report in
Nature on 11 April 1970 about single crystals of a valine-specific tRNA from yeast1. We find that
the diffraction pattern attributed to valyl tRNA...

Nature 303, 195 - 195 (19 May 1983) Correspondence

2. A reply from Paradies

H.H. PARADIES

Nature 303, 196 - 196 (19 May 1983) Correspondence

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: The importance of USING our validation tools
From: Peter Keller pkeller {- at -} GLOBALPHASING {- dot -} COM
Date: 2007-08-16

Next message:
Subject: Re: The importance of USING our validation tools
From: "Mark J {- dot -} van Raaij" vanraaij {- at -} USC {- dot -} ES
Date: 2007-08-16