[ccp4bb] The importance of USING our validation tools

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

- CCP4BB

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: C3b, validation, deposition diffraction images
From: Luca Jovine luca {- dot -} jovine {- at -} BIOSCI {- dot -} KI {- dot -} SE
Date: 2007-08-17

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Subject: Public forums
From: "Hurley, Thomas D {- dot -} " thurley {- at -} IUPUI {- dot -} EDU
Date: 2007-08-17

Subject: The importance of USING our validation tools
From: vanraaij {- at -} USC {- dot -} ES vanraaij {- at -} USC {- dot -} ES
Date: 2007-08-17

how about this scenario:
the structure really is as published, or very like it, but upon
refinement, R-factors were high, other indicators were dodgy etc. so
the authors were afraid to publish as is and made up a dataset to
support their structure - this would be a bit less bad.

let's see how the authors, Nature (and the other journals) respond.
As some remarked, this is important, because if we let it pass, it
could damage the prestige of protein crystallography. I think, as the
crystallographic community, we should quickly act to put proper
controls in place like submission of raw images etc.
Mark

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: C3b, validation, deposition diffraction images
From: Luca Jovine luca {- dot -} jovine {- at -} BIOSCI {- dot -} KI {- dot -} SE
Date: 2007-08-17

Next message:
Subject: Public forums
From: "Hurley, Thomas D {- dot -} " thurley {- at -} IUPUI {- dot -} EDU
Date: 2007-08-17