Re: [ccp4bb] R-sleep

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CCP4bb <-- 2007 <-- October 2007 <-- 01 October 2007

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Subject: Re: R-sleep
From: Ethan Merritt merritt {- at -} U {- dot -} WASHINGTON {- dot -} EDU
Date: 2007-10-01

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Date: 2007-10-01

Subject: Re: R-sleep
From: William Scott wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2007-10-01

If R-sleep is to be the "real" validation R-factor, why not just sequester
each of R-sleep and the current R-free, each as a randomly-chosen (but
mutually exclusive) set of reflections, and then proceed as normally with
the other (eg) 80% of the data until the very end of the refinement, using
the R-free set to optimize weightings for geometries, NCS symmetry
averaging, and so forth, and then simply add those back in at the
penultimate step of refinement. In the end, you have R-sleep and the
Rfactor corresponding to the rest of the data, just like before, and you
can have the additional statistic reporting the difference between R-sleep
and and R-free, which we could call something like the R-i-didn't-peak.

Peter Adrian Meyer wrote:
> This raises a slightly tangential question though - how do we know how
> what obs/param ratio is good enough?

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CCP4bb <-- 2007 <-- October 2007 <-- 01 October 2007

Previous message:
Subject: Re: R-sleep
From: Ethan Merritt merritt {- at -} U {- dot -} WASHINGTON {- dot -} EDU
Date: 2007-10-01

Next message:
Subject: Re: [COOT] i need linux help RHE4
From: Kay Diederichs kay {- dot -} diederichs {- at -} UNI-KONSTANZ {- dot -} DE
Date: 2007-10-01