Re: [ccp4bb] Morphing with mutations

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

- CCP4BB

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Postdoc at the Spallation Neutron Source
From: Leighton Coates coatesl {- at -} SNS {- dot -} GOV
Date: 2007-10-02

Next message:
Subject: Structural biologist position available at CrystaX
From: Montse Soler msoler {- at -} CRYSTAX {- dot -} COM
Date: 2007-10-02

Subject: Re: Morphing with mutations
From: Gerard DVD Kleywegt gerard {- at -} XRAY {- dot -} BMC {- dot -} UU {- dot -} SE
Date: 2007-10-02

> Does anybody know, please, any alternative program or trick to transfom the
> side chain of a residues into its mutated counterpart, please, with a nice
> and smooth visual effect? Does LSQMAN, for example, sort this problem out?
> It is not clear to me reading the manual.

no, it won't. however, in certain cases you can fool it into doing silly
transmogrifications like in the animated hic-up logo
(http://xray.bmc.uu.se/hicup/hicup_anim.gif). this was generated as a
Cartesian morph from hetero compound RE9 (in PDB entry 1CBQ) to REA (1CBS).
the two hetero compounds have the same number of heavy atoms, with the same
names.

--dvd

******************************************************************
Gerard J. Kleywegt
[Research Fellow of the Royal Swedish Academy of Sciences]
Dept. of Cell & Molecular Biology University of Uppsala
Biomedical Centre Box 596
SE-751 24 Uppsala SWEDEN

http://xray.bmc.uu.se/gerard/ mailto:gerard@xray.bmc.uu.se
******************************************************************
The opinions in this message are fictional. Any similarity
to actual opinions, living or dead, is purely coincidental.
******************************************************************

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Postdoc at the Spallation Neutron Source
From: Leighton Coates coatesl {- at -} SNS {- dot -} GOV
Date: 2007-10-02

Next message:
Subject: Structural biologist position available at CrystaX
From: Montse Soler msoler {- at -} CRYSTAX {- dot -} COM
Date: 2007-10-02