- Protein crystallography
Main steps: - Protein purification - Crystallisation
Special: - Programs for crystallography - X-ray detectors
Basic tutorials: - Chemistry - Protein - Peptide - Amino Acids
Xtal community: - CCP4BB
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Subject: Dissolving s-adenosylhomocysteine From: Ray Changrui Lu changrui {- at -} GMAIL {- dot -} COM Date: 2007-11-06
Hi all,
I am in the process of obtaining crystals in complex with s-adenosylhomocysteine but this compound doesn't dissolve in normal pH. The final concentration needs to be in mM range so the stock ideally needs to be at least 50mM. I know SAH is quite soluble in DMSO but is there anyway to get it in aqueous solution without organic solvent or strong acid? Thank you very much in advance.
Ray
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