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[ccp4bb] Off-topic structural genomics related question.
 

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CCP4bb <-- 2008 <-- March 2008 <-- 18 March 2008
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From: James Stroud jstroud {- at -} MBI {- dot -} UCLA {- dot -} EDU
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Subject: Re: Off-topic structural genomics related question.
From: "Das, Debanu" debanu {- at -} SLAC {- dot -} STANFORD {- dot -} EDU
Date: 2008-03-18


Subject: Off-topic structural genomics related question.
From: Ramaswamy rams {- at -} POORI {- dot -} BIOCHEM {- dot -} UIOWA {- dot -} EDU
Date: 2008-03-18
Hello all,

I apologize for this slightly off topic structural genomics kind of
question(s).

The number of structures deposited in the PDB is increasing, the number
of groups doing structural work is also increasing. Given these two
scenarios - how much has efficiency increased? We know average quality
has not improved :-)

Question posed in a different way - One experienced crystallographer is
being supplied with crystals of proteins - how many can one solve in a
year (40 hour weeks, with 5 week holidays).

Assumptions:
1. The average size of the protein is 250 amino acids.
2. All are MAD structures with Se-Met readily available
3. Beam time is not bottle neck.
4. Average resolution 2.3-2.5 (so, there are some at 3.0 and some at
1.5A resolution).

May be some of the SG groups or PX beamlines have already computed
numbers like these. I would appreciate if they are shared with me
(along with the assumptions that have gone into the calculations).

Thanks.

Rams.
S. Ramaswamy.
Department of Biochemistry
University of Iowa.

CCP4bb navigation

CCP4bb <-- 2008 <-- March 2008 <-- 18 March 2008
Previous message:
Subject: Re: 3D mouse?
From: James Stroud jstroud {- at -} MBI {- dot -} UCLA {- dot -} EDU
Date: 2008-03-18 		Next message:
Subject: Re: Off-topic structural genomics related question.
From: "Das, Debanu" debanu {- at -} SLAC {- dot -} STANFORD {- dot -} EDU
Date: 2008-03-18


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