Re: [ccp4bb] Inverse 3D profile/threading

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

Basic tutorials:

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   - Amino Acids

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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From: Bart Hazes bart {- dot -} hazes {- at -} UALBERTA {- dot -} CA
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Subject: Re: Inverse 3D profile/threading
From: Mensur Dlakic mdlakic {- at -} MONTANA {- dot -} EDU
Date: 2008-04-02

Hi Jason,

RosettaDesign server will do just that:

http://rosettadesign.med.unc.edu/

You can specify that certain residues remain unchanged (say active site),
that they fall into defined physico-chemical categories (polar, hyrophobic,
etc), or let the server change all residues into whatever is compatible
with your original structure.

If you want a stand-alone version of Rosetta:

http://depts.washington.edu/ventures/UW_Technology/Express_Licenses/Rosetta/

At 06:45 AM 4/2/2008, Jason Greenwald wrote:
>I am looking for software or a server to run the 3D-1D profile search
>in reverse: that is I have a new structure (not in yet deposited in
>PDB) and I want to see what sequences might fit well to this 3D
>structure.
>Can someone point me in the right direction?
>
>-jason

==========================================================================

Mensur Dlakic, PhD
Tel: (406) 994-6576

Department of Microbiology
Fax: (406) 994-4926

Montana State University
Lab: (406) 994-6237

109 Lewis Hall, P.O. Box 173520
http://myprofile.cos.com/mensur

Bozeman, MT 59717-3520
E-mail: mdlakic@montana.edu

==========================================================================

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: twinned?
From: Bart Hazes bart {- dot -} hazes {- at -} UALBERTA {- dot -} CA
Date: 2008-04-02

Next message:
Subject: Re: Co-expression plasmids
From: P Hubbard dienoylcoa {- at -} HOTMAIL {- dot -} COM
Date: 2008-04-02