[ccp4bb] question on how crystals form

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Summary: Negative density around COOH
From: Narayanan Ramasubbu ramasun1 {- at -} UMDNJ {- dot -} EDU
Date: 2008-05-05

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Date: 2008-05-05

Subject: question on how crystals form
From: Michael Colaneri colanerim {- at -} GMAIL {- dot -} COM
Date: 2008-05-05

Dear colleagues,

I have a structure with two identical dimers per asymmetric unit. If the
dimers are identical in different crystalline environments and in different
crystal forms they should be particularly stable.

How does such a stable dimer crystallize? Is it necessay to pre-exist in
the specific conformation in solution (even to a lesser extent than a major
monomeric form) or a very stable dimer can assemble from the very beginning
durnig crystallization? And can the same dimer form during crystallization
in different crystalline environments without it being present in solution
to any (even infinitesimal) extent?

I would appreciate all responses.

Thanks.

Mike Colaneri

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Summary: Negative density around COOH
From: Narayanan Ramasubbu ramasun1 {- at -} UMDNJ {- dot -} EDU
Date: 2008-05-05

Next message:
Subject: HKL2000 and gcc4
From: Chris Waddling waddling {- at -} MSG {- dot -} UCSF {- dot -} EDU
Date: 2008-05-05