[ccp4bb] Multimer threading server

- Protein crystallography

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: Using DM for density averaging.
From: Kevin Cowtan cowtan {- at -} YSBL {- dot -} YORK {- dot -} AC {- dot -} UK
Date: 2008-06-03

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Subject: Re: Multimer threading server
From: Gerard DVD Kleywegt gerard {- at -} XRAY {- dot -} BMC {- dot -} UU {- dot -} SE
Date: 2008-06-03

Subject: Multimer threading server
From: Andrew Torelli andrew_torelli {- at -} URMC {- dot -} ROCHESTER {- dot -} EDU
Date: 2008-06-03

To the CCP4 community,

I have a sequence that I would like to model by threading onto each subunit of a homo-tetramer of a related protein (crystal structure). It doesn't work to thread each subunit individually and then 'recombine' the homodimer as a single PDB because the interfaces suffer from clashes and overlaps. Does anyone know of a server that can peform multimer threading based on a sequence and a multimeric crystal structure?

Thank you for the advice,
Best Regards,
-Andy Torelli

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: Using DM for density averaging.
From: Kevin Cowtan cowtan {- at -} YSBL {- dot -} YORK {- dot -} AC {- dot -} UK
Date: 2008-06-03

Next message:
Subject: Re: Multimer threading server
From: Gerard DVD Kleywegt gerard {- at -} XRAY {- dot -} BMC {- dot -} UU {- dot -} SE
Date: 2008-06-03