[ccp4bb] Post doctoral positions in Structural Immunology

- Protein crystallography

Main steps:

- Protein purification
- Crystallisation

Special:

- Programs for crystallography
- X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

- CCP4BB

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: Protein expression in Minimal media (M9)
From: Eric Toth etoth001 {- at -} UMARYLAND {- dot -} EDU
Date: 2007-04-19

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Subject: Re: Protein expression in Minimal media (M9)
From: jwallen {- at -} CSB {- dot -} WFU {- dot -} EDU jwallen {- at -} CSB {- dot -} WFU {- dot -} EDU
Date: 2007-04-19

Subject: Post doctoral positions in Structural Immunology
From: Steve Almo almo {- at -} MEDUSA {- dot -} BIOC {- dot -} AECOM {- dot -} YU {- dot -} EDU
Date: 2007-04-19

------------------- STRUCTURAL IMMUNOLOGY ----------------------

Positions are now available to study the structure, function and
therapeutic application of T cell costimulatory molecules in the Nathenson
and Almo laboratories at the Albert Einstein College of Medicine. We
employ a multi-disciplinary approach that includes traditional high
resolution crystallography, fluorescence microscopy, FRET, cell-based and
whole animal studies. The ideal candidate will have considerable
experience in protein production in both bacterial and eukaryotic
platforms and a strong interest in defining the fundamental mechanisms
that modulate the cellular immune response.

These positions are supported by an NIH-funded Training Grant in
Immuno-Oncology and require either US citizenship or permanent residence
status.

Interested individuals should send a CV and arrange for three letters of
reference to be sent to muran@aecom.yu.edu.

Representative examples of our program are provided by the following
references:

Schwartz, et al., (2001) Structural Basis for Costimulation by the Human
CTLA-4/B7-2 Complex. Nature 410: 604-608.

Zhang, X., et al. (2004) Structural and Functional Analysis of the
Costimulatory Receptor Programmed Death-1. Immunity 20: 337-347.

Bhatia, S., et al. (2005) Different Cell Surface Oligomeric States of B7-1
and B7-2: Implications for Signaling. Proc. Natl. Acad. Sci. USA 102:
15569-15574.

Cao, E., et al. (2006) NTB-A Crystal Structure: Implications for
Homophilic Interactions and Signaling by the SLAM Family of Receptors.
Immunity 25:559-570.

Chattopadhyay, K., et al. (2006) Structural basis of inducible
costimulator ligand costimulatory function: determination of the cell
surface oligomeric state and functional mapping of the receptor binding
site of the protein. J Immunol. 177:3920-3929.

Cao, E., et al. (2007), T cell immunoglobulin mucin-3 crystal structure
reveals a galectin-9-independent ligand-bindng surface, Immunity
26:311-21.

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: Protein expression in Minimal media (M9)
From: Eric Toth etoth001 {- at -} UMARYLAND {- dot -} EDU
Date: 2007-04-19

Next message:
Subject: Re: Protein expression in Minimal media (M9)
From: jwallen {- at -} CSB {- dot -} WFU {- dot -} EDU jwallen {- at -} CSB {- dot -} WFU {- dot -} EDU
Date: 2007-04-19