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Re: [ccp4bb] Crystallogrphy today

- Protein crystallography

Main steps:

   - Protein purification
   - Crystallisation

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   - X-ray detectors

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CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: Re: Crystallogrphy today
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2008-09-21
Next message:
Subject: Re: Crystallogrphy today
From: Artem Evdokimov artem {- at -} XTALS {- dot -} ORG
Date: 2008-09-21


Subject: Re: Crystallogrphy today
From: Richard Gillilan reg8 {- at -} CORNELL {- dot -} EDU
Date: 2008-09-21

>
>>
>> 6.cryo crystallography
>
> This is routine.

Well maybe there are still some surprises. Consider the case of high-
pressure cooling.

>
>>
>> 8.radiation damage
>
> see cryocrystallography, and take lots of vitamin C

There may be some surprises here too as one looks at smaller crystals
with smaller beams.

>>

Just a few other comments. Students starting out now in this field
may have the opportunity to work with the next-generation x-ray
sources such as FEL's and ERL's. These sources are not just brighter
than the current synchrotrons. They will provide fully-coherent, high
spectral brilliance x-rays in shorter pulses than are currently
available. A number of novel techniques are being proposed that will
take advantage of these kinds of beams, but who knows what
opportunities wait in the future for the next highly-motivated
student. One place to start looking is "coherent diffraction
imaging" ... I think C. Riekel et. al. just published a Phys Rev
Letter on this subject.


Richard Gillilan
MacCHESS


CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: Re: Crystallogrphy today
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2008-09-21
Next message:
Subject: Re: Crystallogrphy today
From: Artem Evdokimov artem {- at -} XTALS {- dot -} ORG
Date: 2008-09-21



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