Re: [ccp4bb] site mutation evaluation

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: site mutation evaluation
From: Hongmin Zhang hongmin {- at -} RED {- dot -} DFCI {- dot -} HARVARD {- dot -} EDU
Date: 2008-12-02

Subject: Re: site mutation evaluation
From: Juergen Bosch jbosch {- at -} U {- dot -} WASHINGTON {- dot -} EDU
Date: 2008-12-02

Pymol
the question is, into how much trouble do you want to get ?
MD simulations ? Energy minimisation ? Then you will need to do more
than just mutate on the sreen one residue with Pymol.

Jürgen

On 2 Dec 2008, at 17:29, Hongmin Zhang wrote:

> Dear All,
> I am trying to mutate a single amino acid in a PDB to see if the
> mutant
> disturbs ligand binding. Does anyone know any software that can do
> such work?
> Thanks a lot!

-
Jürgen Bosch
University of Washington
Dept. of Biochemistry, K-426
1705 NE Pacific Street
Seattle, WA 98195
Box 357742
Phone: +1-206-616-4510
FAX: +1-206-685-7002
Web: http://faculty.washington.edu/jbosch

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Next message:
Subject: Re: site mutation evaluation
From: Hongmin Zhang hongmin {- at -} RED {- dot -} DFCI {- dot -} HARVARD {- dot -} EDU
Date: 2008-12-02