[ccp4bb] How to chemically modify the side chain of Glu?

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CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

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Subject: Re: ccp4-6.1.1 for OS X (fink)
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2009-02-08

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From: Alpharyun_Ni alpharyun {- at -} GMAIL {- dot -} COM
Date: 2009-02-08

Subject: How to chemically modify the side chain of Glu?
From: Jiamu Du jiamudu {- at -} GMAIL {- dot -} COM
Date: 2009-02-08

Dear All,
Sorry for an off topic question.
I am studying a transmembrane protein. An extracellular Glu residue might be
the key residue for its function. The mutation experiment results some
unfavourable effects.
So I want to find some chemicals which can modified the sidechain of Glu or
neutralize its negative charge at least. While these chemicals should not
have cytotoxic effects to cell. Because the experiment must be carried out
with live cells.
Is there any suggestions or references?

Thanks.

--
Jiamu Du, Ph.D.
State Key Laboratory of Molecular Biology
Institute of Biochemistry and Cell Biology
Shanghai Institutes for Biological Sciences
Chinese Academy of Sciences
320 Yue-Yang Road
Shanghai 200031
P. R. China
Tel: +86-21-5492-1117
E-mail: jiamudu@gmail.com

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999

Previous message:
Subject: Re: ccp4-6.1.1 for OS X (fink)
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2009-02-08

Next message:
Subject: refinment of mir anomalous data in MLPHARE
From: Alpharyun_Ni alpharyun {- at -} GMAIL {- dot -} COM
Date: 2009-02-08