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[ccp4bb] Announcement: Fragment Screening Library for X-ray Crystallography
- Protein crystallography

Main steps:

   - Protein purification
   - Crystallisation

Special:

   - Programs for crystallography
   - X-ray detectors

Basic tutorials:

   - Chemistry
   - Protein
   - Peptide
   - Amino Acids

Xtal community:

   - CCP4BB

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: Re: elbow and compound library
From: Nigel W Moriarty NWMoriarty {- at -} LBL {- dot -} GOV
Date: 2009-03-03		Next message:
Subject: Re: elbow and compound library
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2009-03-03


Subject: Announcement: Fragment Screening Library for X-ray Crystallography
From: John Badger jbadger1 {- at -} SAN {- dot -} RR {- dot -} COM
Date: 2009-03-03

Zenobia Therapeutics is now providing a fragment screening library
suitable for use with protein crystallography.

The library contains a diverse set 352 small molecule compounds with a
mean molecular weight of 155 Da. The chemical compound types
(typically, simple decorated rings) are suitable for efficiently probing
protein sites to determine binding substructures for lead discovery. The
compounds in the library are pre-plated so as to provide 100uL of each
compound at 200mM concentration. All compounds have been tested to
ensure adequate solubility in DMSO.

To simplify the experimental design and interpretation of fragment
screening experiments with mixtures the compounds are organized in to
shape-diverse groups and 3D structure models of all compounds are
provided.

For additional information on Zenobia Therapeutics, Inc., contact Dr.
Vicki Nienaber at vicki@zenobiatherapeutics.com or visit
www.zenobiatherapeutics.com. For additional information on Zenobia's
fragment library, contact Dr. John Badger at
john@zenobiatherapeutics.com.

John Badger, Director of Structural Biology, Zenobia Therapeutics
http://www.zenobiatherapeutics.com/

CCP4bb navigation

CCP4bb <-- 1999 <-- November 1999 <-- 30 November 1999
Previous message:
Subject: Re: elbow and compound library
From: Nigel W Moriarty NWMoriarty {- at -} LBL {- dot -} GOV
Date: 2009-03-03		Next message:
Subject: Re: elbow and compound library
From: "William G {- dot -} Scott" wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2009-03-03
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