[ccp4bb] Mol Rep in high symmetry spacegroups

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CCP4bb <-- 2007 <-- May 2007 <-- 12 May 2007

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Subject: Re: Superdex 200 PC columns
From: Miguel Ortiz-Lombardia molatwork {- at -} YAHOO {- dot -} ES
Date: 2007-05-12

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Subject: Re: Mol Rep in high symmetry spacegroups
From: Roger Rowlett RRowlett {- at -} MAIL {- dot -} COLGATE {- dot -} EDU
Date: 2007-05-12

Subject: Mol Rep in high symmetry spacegroups
From: Jay Thompson jay {- dot -} xtalman {- at -} GMAIL {- dot -} COM
Date: 2007-05-12

Hi All,

I have a question- kinda general though. I've always heard of stories from
people that molecular replacement is often difficult in high symmetry space
groups, like R32, cubic, etc... I'm not quite sure I understand why that is
the case? Is the molecular replacement difficult because in high symmetry
space groups you have so many molecules in the unit cell and therefore the
patterson vectors becomes more complicated and therefore more difficult to
find a match during cross rotation/translation? If this is the case, I'm
wondering if this is still a problem with today's computers and software?
Do people have a favorite molecular replacement program they like to use
specifically in high symmetry space groups? or are there programs that
don't handle high symmetry space groups very well? Do people have a
preference between Amore, Phaser, MolRep, epmr, and CNS? Any anecdotes
would be appreciated. Thanks in advance!

Jay

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CCP4bb <-- 2007 <-- May 2007 <-- 12 May 2007

Previous message:
Subject: Re: Superdex 200 PC columns
From: Miguel Ortiz-Lombardia molatwork {- at -} YAHOO {- dot -} ES
Date: 2007-05-12

Next message:
Subject: Re: Mol Rep in high symmetry spacegroups
From: Roger Rowlett RRowlett {- at -} MAIL {- dot -} COLGATE {- dot -} EDU
Date: 2007-05-12