[ccp4bb] Protein crystallographer position in Novartis, Basel

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CCP4bb <-- 2007 <-- May 2007 <-- 15 May 2007

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From: Tim Grune tim {- dot -} grune {- at -} SYNCHROTRON {- dot -} VIC {- dot -} GOV {- dot -} AU
Date: 2007-05-15

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Subject: Protein crystallographer position in Novartis, Basel
From: sandra {- dot -} jacob {- at -} NOVARTIS {- dot -} COM sandra {- dot -} jacob {- at -} NOVARTIS {- dot -} COM
Date: 2007-05-15

Novartis Institutes of Biomedical Research in Basel, Switzerland are
looking for a motivated individual to fill the role of a Research
Investigator in protein crystallography.

The protein crystallographer will work in a biomolecular structure group
dedicated to the production of structural data to support drug discovery
programs in a wide variety of therapeutic indications. The job consists of
the planning of gene-to-structure projects, the running of the
crystallisation, data collection and structure determination efforts, and
the presentation of the results obtained. Additional activities may
include protein purification and studies of protein-ligand interactions
using other biophysical methods (eg. ITC, DSC). The candidate will be
expected to have an interest in fragment-based screening, exploring new
ideas and implementing novel technologies. Good leadership and
communication skills are essential as each research investigator has a
role in coordinating the activities of a team to bring a drug target from
given sequence to three-dimensional structure and to ensure the maximum
impact of the structural work in the multidisciplinary drug discovery
teams.

The protein structure unit consists of experts in all areas from cloning
to structural studies by X-ray and NMR. Specialist support in these areas
is available as are state of the art equipment (well equipped purification
labs, crystallisation and imaging robotics, Fr-E generator with sample
changer and CCD and image plate detectors, and linux workstations with a
large range of software) and excellent access to a synchrotron radiation
source. Dedicated support for software and hardware is also available.

Requirements:
Education and training : PhD in structural biology, biochemistry,
chemistry or related science
Specific expertise : Protein X-ray crystallography, protein preparation,
other biophysical techniques would be an advantage
Necessary job experience : >1 years of postdoc studies, several years
industrial experience including fragment-based screening would be an
advantage
General : Scientific and entrepreneurial initiative, team player,
communication skills
Languages : English a must, German desirable

A global healthcare leader, Novartis has one of the most exciting product
pipelines in the industry today. A pipeline of innovative medicines
brought to life by diverse, talented, performance driven people. All of
which makes us the most rewarding employer in our field.

Applications for this position must be submitted via the Novartis Careers
web page: www.novartis.com quoting position number 27952BR.

Sandra Jacob
Novartis Pharma AG
DT/PSU: Unit head of Biomolecular Structure
CHBS, WSJ-088.9.08A
Novartis Pharma AG
Forum 1
Novartis Campus
CH-4056 Basel
Switzerland
Phone: +41 61 3249844
Fax: +41 61 3242686
Email : sandra.jacob@novartis.com

CCP4bb navigation

CCP4bb <-- 2007 <-- May 2007 <-- 15 May 2007

Previous message:
Subject: Re: crystallographic magic
From: Tim Grune tim {- dot -} grune {- at -} SYNCHROTRON {- dot -} VIC {- dot -} GOV {- dot -} AU
Date: 2007-05-15

Next message:
Subject: Hydrogens disappear after refmac refinement
From: "R {- dot -} P {- dot -} Joosten" rjoosten {- at -} CMBI {- dot -} RU {- dot -} NL
Date: 2007-05-15