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[ccp4bb] Post-doctoral position Edwards lab University of Leeds
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Subject: Post-doctoral position Edwards lab University of Leeds
From: Thomas Edwards T {- dot -} A {- dot -} Edwards {- at -} LEEDS {- dot -} AC {- dot -} UK
Date: 2007-05-20



<>
Faculty of Biological Sciences
Institute of Molecular & Cellular Biology
Astbury Centre for Structural Molecular Biology

Research Fellow: University Grade 6/7 (£21,682 - £26,666 p.a)
Project Title: The Structure of Dazl based translation control complexes
Job ref 313168 Closing date 15/6/07

We are seeking outstanding and motivated candidates for a postdoctoral position in the laboratory of Dr Thomas Edwards within the Astbury Centre for Structural Molecular Biology at the University of Leeds. The focus of the project is the structure and function of proteins that control translation from mRNAs during germ cell development. Crystallographic studies will be used to investigate the RNA binding and translation control properties of DAZ family proteins and associated cofactors. Molecular biology, protein expression and purification, and X-ray crystallography will be required to pursue this project.

The Fellow's research will benefit from the outstanding resources in the Astbury Centre for Structural Molecular Biology at Leeds. The X-ray facilities include an Raxis IV, with Osmic mirrors and Oxford cryostream, on a Rigaku rotating copper anode X-ray generator. Additionally, there will be regular synchrotron access at Daresbury, DIAMOND and Grenoble. A state-of-the-art robotic crystallization facility includes liquid handling and nano-liter drop-setting. Protein expression and purification facilities include tissue culture, facilities for bacterial and insect cell growth, and Åkta purification systems.

Leeds is an exciting multi-cultural city that is the fastest growing in England. It is unrivalled in the north of England as a major shopping destination and centre for the arts, entertainment, nightlife and leisure. The city has a rich cultural heritage with a wide range of theatres, cinemas, museums and art galleries and a thriving music scene to cater for all tastes. Leeds has a proud sporting tradition and there are plenty of opportunities to participate at all levels. Nature lovers will enjoy the nearby Yorkshire Moors and Dales and find other outdoor recreation easily accessible.

For details of the Edwards lab see http://www.bmb.leeds.ac.uk/staff/tae/. Please direct informal enquiries to t.a.edwards@leeds.ac.uk. To apply online please visit http://www.leeds.ac.uk/about/jobs/ and click on jobs. Alternatively, application packs are available from Mr A Bateman, Faculty Staff Recruitment Office, tel 0113 343 8040, email fbsjobs@leeds.ac.uk



______________
T.Edwards Ph.D.
Astbury Centre for Structural Molecular Biology
University of Leeds, Leeds, LS2 9JT
Telephone: 0113 343 3031
http://www.bmb.leeds.ac.uk/staff/tae/
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